Prevalence of Neonatal Jaundice and its Associated Risk Factors in Babies Born At Westend Hospital In Harare, Zimbabwe

Authors

  • Chiwoniso Mitchelle Kahiya Universidad de África.
  • Abdoul Razak Mahaman Yacoubou Tonji medical college huazhong university of science and technology Wuhan, China
  • Mahamane Salissou Maibouge Tanko Africa University

Abstract

Introduction: Neonatal jaundice is a common condition worldwide occurring in up to 60% of healthy term babies and 80% of preterm babies within the first week of life. Its risk factors are mainly demographic, maternal, and neonatal. Zimbabwe currently lacks sufficient data on these. Objective: The present report aimed to determine the prevalence and risk factors of neonatal jaundice in babies born at Westend Hospital Zimbabwe in 2021. Methods:  This was an analytical cross-sectional study of secondary data from the year 2021.  Out of 1172 babies delivered, only 611 babies met the inclusion criteria for the study; all babies on medication and pregnant women under the age of 18 years were excluded.  Case notes of babies admitted from January 2021 to December 2021 were retrieved through information on bio data. Using convenient sampling, 611 babies were found to meet the criteria for the study, through an assessment of their demographic profiles, clinical outcomes, and laboratory data. Additionally, descriptive statistics were used. Maternal and fetal risk factors were assessed, P< 0.05 set as statistically significant. Results: This study showed that 281 babies presented neonatal jaundice, yielding a 45.99% prevalence rate. A significant relationship was found between neonatal jaundice and the predisposing risk factors, namely, low birth weight (p=<0.0001), prematurity (p=<0.0001), neonatal gender (p=0.028), blood group incompatibility (p=<0.001), G6PD deficiency   (p=0.001), black race (P<0.0001), maternal diabetes (P<0.0001) lack of breastfeeding and history of jaundice in the family (P<0.002). Conclusions:  The prevalence of neonatal jaundice was found to be high and risk factors were found to be predominantly demographic, maternal, and neonatal. Keywords: Neonatal, Jaundice, Risk, Maternal, Prevalence

Author Biographies

Chiwoniso Mitchelle Kahiya, Universidad de África.

Universidad de África.

Abdoul Razak Mahaman Yacoubou, Tonji medical college huazhong university of science and technology Wuhan, China

Tonji medical college huazhong university of science and technology Wuhan, China

Mahamane Salissou Maibouge Tanko, Africa University

Africa University

 

References

Slusher TM, Angyo IA, Bode-Thomas F, Akor F, Pam SD, Adetunji AA, et al. Transcutaneous Bilirubin Measurements and Serum Total Bilirubin Levels in Indigenous African Infants. American Academy of Pediatrics. 2004;113(6):1636-41.

Olusanya BO, Kaplan M, Hansen TWR. Neonatal hyperbilirubinaemia: a global perspective. The Lancet Child & Adolescent Health. 2018;2(8):610-20.

Chimhuya S, Mbuwayesango B, Aagaard EM, Nathoo KJ. Development of a neonatal curriculum for medical students in Zimbabwe – a cross sectional survey. BMC Medical Education. 2018;18(1):90.

Pace EJ, Brown CM, DeGeorge KC. Neonatal hyperbilirubinemia: An evidence-based approach. Journal of Family Practiice. 2019;68(1):E4-E11.

Mugadza G, Zvinavashe M, Gumbo Z, Stray-Pedersen B. Early breastfeeding initiation and incidence of severe neonatal jaundice in Chipinge district Zimbabwe. International Journal of Contemporary Pediatrics. 2017;4(6):1922.

Maisels MJ, Kring E. The Contribution of Hemolysis to Early Jaundice in Normal Newborns. American Academy of Pediatrics. 2006;118(1):276-9.

Bhutani VK, Zipursky A, Blencowe H, Khanna R, Sgro M, Ebbesen F, et al. Neonatal hyperbilirubinemia and Rhesus disease of the newborn: incidence and impairment estimates for 2010 at regional and global levels. Pediatric Research. 2013;74(1):86-100.

Porter ML, Dennis BL. Hyperbilirubinemia in the term newborn. Am Fam Physician. 2002;65(4):599-606.

Tikmani SS, Warraich HJ, Abbasi F, Rizvi A, Darmstadt GL, Zaidi AKM. Incidence of neonatal hyperbilirubinemia: a population-based prospective study in Pakistan. Tropical Medicine & International Health. 2010;15(5):502-7.

Kumar K, Sohaila A, Tikmani SS, Khan IA, Zafar A. Screening for G6PD Deficiency Among Neonates with Neonatal Jaundice Admitted to Tertiary Care Center: A Need in Disguise. J Coll Physicians Surg Pak. 2015;25(8):625-6.

Boskabadi H, Rakhshanizadeh F, Zakerihamidi M. Evaluation of Maternal Risk Factors in Neonatal Hyperbilirubinemia. Archieves of Iran Medicine. 2020;23(2):128-40.

Weng Y-H, Cheng S-W, Yang C-Y, Chiu Y-W. Risk assessment of prolonged jaundice in infants at one month of age: A prospective cohort study. Scientific Reports. 2018;8(1):14824.

Devi DS, Vijaykumar B. Risk factors for neonatal hyperbilirubinemia: a case control study. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2017;6:198+.

Rougée LR, Miyagi SJ, Collier AC. Obstetric Obesity is Associated with Neonatal Hyperbilirubinemia with High Prevalence in Native Hawaiians and Pacific Island Women. Hawaii J Med Public Health. 2016;75(12):373-8.

Mohammad-Beigi A, Tabatabaee SHR, Yazdani M, Mohammad-salehi N. Gestational diabetes related unpleasant outcomes of pregnancy. FEYZ. 2007;11(1):33-8.

Zarrinkoub F, Beigi A. Epidemiology of hyperbilirubinemia in the first 24 hours after birth. Tehran-Univ-Med-J. 2007;65(6):54-9.

Published

2023-07-11

How to Cite

Kahiya, C. M., Mahaman Yacoubou, A. R., & Maibouge Tanko, M. S. (2023). Prevalence of Neonatal Jaundice and its Associated Risk Factors in Babies Born At Westend Hospital In Harare, Zimbabwe. Medicina Social Social Medicine, 16(2), 57–64. Retrieved from https://www.socialmedicine.info/index.php/medicinasocial/article/view/1561

Issue

Section

Investigación Original